IL-3 beta Protein

Catalog No. ABIN2468669

This Recombinant IL-3 beta protein is produced in Escherichia coli (E. coli).

Quick Overview for IL-3 beta Protein (ABIN2468669)

Target: IL-3 beta (Interleukin 3 beta (IL-3 beta))

Protein Type: Recombinant

Biological Activity: Active

Origin: Rat

Source: Escherichia coli (E. coli)

Purity: < 98 % by SDS-PAGE gel and HPLC analyses.

Product Details

Sequence: MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC

Characteristics: The ED50 was determined by the dose - dependent stimulation of the proliferation of thymidine uptake by murine MC - 9 cells is < 10 ng/mL, corresponding to a specific activity of >1.0 x 10⁵ units/mg.

Endotoxin Level: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Handling Advice: As with any protein, exposing IL-3 beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -20 °C

Storage Comment: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-3 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Expiry Date: 24 months

Target Details

Target: IL-3 beta (Interleukin 3 beta (IL-3 beta))

Alternative Name: IL-3 beta

Background: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant rat IL-3beta is a 16.3 kDa globular protein containing 144 amino acid residues.

Gene ID: 171081

NCBI Accession: NP_598239

OMIM: 19424232

UniProt: Q78ZF5